Interactions between UCP2 SNPs and telomere length exist in the absence of diabetes or pre-diabetes

@inproceedings{Zhou2016InteractionsBU,
  title={Interactions between UCP2 SNPs and telomere length exist in the absence of diabetes or pre-diabetes},
  author={Yuling Zhou and David Simmons and Brett D. Hambly and Craig S. McLachlan},
  booktitle={Scientific reports},
  year={2016}
}
Mitochondrial uncoupling protein 2 (UCP2) can affect oxidative stress levels. UCP2 polymorphisms are associated with leukocyte telomere length (LTL) in Type 2 Diabetes, which also induces considerable background oxidative stress. The effects of UCP2 polymorphisms on LTL in populations without diabetes have not been well described. Our aims are to evaluate the interaction between LTL and UCP2 polymorphisms in 950 subjects without diabetes. The monochrome multiplex quantitative PCR method was… CONTINUE READING