Interactions between ORG9426 and other non-depolarizing neuromuscular blocking agents in ratsin vivo

@article{Watanabe2010InteractionsBO,
  title={Interactions between ORG9426 and other non-depolarizing neuromuscular blocking agents in ratsin vivo},
  author={Kazuhiko Watanabe},
  journal={Journal of Anesthesia},
  year={2010},
  volume={6},
  pages={277-283}
}
In this study, combined neuromuscular blocking effects of ORG9426 with other non-depolarizing neuromuscular blocking agents were investigated. About 20% steady state neuromuscular block was established by a continuous infusion of one of 6 neuromuscular blocking agents (ORG9426, vecuronium, pancuronium, pipecuronium, d-tubocurarine and metocurine). Then 1/7 of the ED50 of ORG9426 or one of other neuromuscular blocking agents was administered in a single injection, and the increase in the… Expand
Pharmacoeconomics and Pharmacodynamic Interactions of Rocuronium and Pancuronium
TLDR
The combination of P and R provides rapid and smooth intubation with minimal hemodynamic changes at a reasonably priced cost. Expand

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