Interactions between Hsp90 and oncogenic viruses: implications for viral cancer therapeutics.

@article{Defee2011InteractionsBH,
  title={Interactions between Hsp90 and oncogenic viruses: implications for viral cancer therapeutics.},
  author={Michael R Defee and Zhiqiang Qin and Lu Dai and Jennifer S. Isaacs and Chris H. Parsons},
  journal={American journal of cancer research},
  year={2011},
  volume={1 6},
  pages={763-72}
}
Oncogenic viruses are the etiologic agents for a significant proportion of human cancers, but effective therapies and preventative strategies are lacking for the majority of virus-associated cancers. Targeting of virus-induced signal transduction or virus-host protein interactions may offer novel therapeutic strategies for viral cancers. Heat shock protein 90 (Hsp90) is a well-characterized, multifunctional molecular chaperone involved in regulation of signal transduction, transcriptional… CONTINUE READING