Interactions between GH, IGF-I, Glucocorticoids, and Thyroid Hormones during Skeletal Growth

Abstract

Linear growth occurs during development and the childhood years until epiphyseal fusion occurs. This process results from endochondral ossification in the growth plates of long bones and is regulated by systemic hormones and paracrine or autocrine factors. The major regulators of developmental and childhood growth are GH, IGF-I, glucocorticoids, and thyroid… (More)
DOI: 10.1203/00006450-200208000-00003

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