Interactions between β2-syntrophin and a family of microtubule-associated serine/threonine kinases

@article{Lumeng1999InteractionsB,
  title={Interactions between β2-syntrophin and a family of microtubule-associated serine/threonine kinases},
  author={Carey N Lumeng and Stephanie N Phelps and Gregory E. Crawford and Paul D. Walden and Kate F. Barald and Jeffrey S. Chamberlain},
  journal={Nature Neuroscience},
  year={1999},
  volume={2},
  pages={611-617}
}
A screen for proteins that interact with β2-syntrophin led to the isolation of MAST205 (microtubule-associated serine/threonine kinase-205 kD) and a newly identified homologue, SAST (syntrophin-associated serine/threonine kinase). Binding studies showed that β2-syntrophin and MAST205/SAST associated via a PDZ–PDZ domain interaction. MAST205 colocalized with β2-syntrophin and utrophin at neuromuscular junctions. SAST colocalized with syntrophin in cerebral vasculature, spermatic acrosomes and… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 55 extracted citations

Structural abnormalities at neuromuscular synapses lacking multiple syntrophin isoforms.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2004
View 5 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 50 references

Nitric oxide articles

J. E. Brenman, D. S. Chao, H. H. Xia, K. Aldape, D. S. Bredt
Cell 82, • 1999

Gene, Protein and Cell Biology (eds

A. Amalfitano, J. A. Rafael, Chamberlain, J. S. in Dystrophin
Lucy, J. A. & Brown, S. C.) 1–26 • 1997

Similar Papers

Loading similar papers…