Interactions between Δ9-tetrahydrocannabinol and μ opioid receptor agonists in rhesus monkeys: discrimination and antinociception

@article{Li2008InteractionsB,
  title={Interactions between Δ9-tetrahydrocannabinol and μ opioid receptor agonists in rhesus monkeys: discrimination and antinociception},
  author={Jun-Xu Li and Lance R. McMahon and Lisa R. Gerak and Ginger L. Becker and Charles P France},
  journal={Psychopharmacology},
  year={2008},
  volume={199},
  pages={199-208}
}
Opioid receptor agonists can enhance some effects of cannabinoid receptor agonists, and cannabinoid receptor agonists can enhance some effects of opioid receptor agonists; however, the generality of these interactions is not established. This study examined interactions between the discriminative stimulus and antinociceptive effects of μ opioid receptor agonists and Δ9-tetrahydrocannabinol (THC) in rhesus monkeys. Neither heroin nor morphine (intravenous (i.v.) or subcutaneous (s.c.)) altered… CONTINUE READING