Interactions and effects of aminophylline, terbutaline sulfate and verapamil on calcium transport across rat diaphragm.

  title={Interactions and effects of aminophylline, terbutaline sulfate and verapamil on calcium transport across rat diaphragm.},
  author={N A Kanj and R E Ayash and Ziyad M.B. Ghazzal and G M Saadeh and Camille F. Nassar},
  journal={General pharmacology},
  volume={18 4},
The effect of terbutaline sulfate on calcium transport across muscle strips isolated from rat diaphragms, and its effect on this process when used in combination with aminophylline was investigated using labelled calcium in a two-compartment system. The results show that terbutaline sulfate causes a dose-dependent increase in intracellular calcium concentration which reached saturation at a terbutaline sulfate concentration of 2 ng/ml. The inclusion of both aminophylline and terbutaline sulfate… Expand
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Digoxin-stimulated calcium transport across rat diaphragm interactions with aminophylline and verapamil.
The effect of increasing calcium concentration in the presence of digoxin and digoxin plus aminophylline in the incubation medium, showed a nonsaturable linear relationship between calcium concentration and intracellular calcium accumulation. Expand
Effects of aminophylline and terbutaline sulfate on the contractility of feline diaphragm.
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Reversal of impaired calcium homeostasis in the rat diaphragm subjected to Monocrotaline-induced pulmonary hypertension.
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Theophylline and aerosolized terbutaline in the treatment of bronchial asthma. Double-blind comparison of optimal doses.
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