Interactions among Ytm1, Erb1, and Nop7 required for assembly of the Nop7-subcomplex in yeast preribosomes.

@article{Tang2008InteractionsAY,
  title={Interactions among Ytm1, Erb1, and Nop7 required for assembly of the Nop7-subcomplex in yeast preribosomes.},
  author={Lan Tang and Aarti Sahasranaman and Jelena Jakovljevic and Erica B Schleifman and John L. Woolford},
  journal={Molecular biology of the cell},
  year={2008},
  volume={19 7},
  pages={
          2844-56
        }
}
In Saccharomyces cerevisiae, more than 180 assembly factors associate with preribosomes to enable folding of pre-rRNA, recruitment of ribosomal proteins, and processing of pre-rRNAs to produce mature ribosomes. To examine the molecular architecture of preribosomes and to connect this structure to functions of each assembly factor, assembly subcomplexes have been purified from preribosomal particles. The Nop7-subcomplex contains three assembly factors: Nop7, Erb1, and Ytm1, each of which is… CONTINUE READING