Interactions Between HERC2, OCA2 and MC1R May Influence Human Pigmentation Phenotype

@article{Branicki2009InteractionsBH,
  title={Interactions Between HERC2, OCA2 and MC1R May Influence Human Pigmentation Phenotype},
  author={Wojciech Branicki and Urszula Brudnik and Anna Wojas-Pelc},
  journal={Annals of Human Genetics},
  year={2009},
  volume={73}
}
Human pigmentation is a polygenic trait which may be shaped by different kinds of gene–gene interactions. Recent studies have revealed that interactive effects between HERC2 and OCA2 may be responsible for blue eye colour determination in humans. Here we performed a population association study, examining important polymorphisms within the HERC2 and OCA2 genes. Furthermore, pooling these results with genotyping data for MC1R, ASIP and SLC45A2 obtained for the same population sample we also… Expand
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