Interaction with lipid II induces conformational changes in bovicin HC5 structure.


Bovicin HC5 is a lantibiotic produced by Streptococcus bovis HC5 that targets the cell wall precursor lipid II. An understanding of the modes of action against target bacteria can help broadening the clinical applicability of lantibiotics in human and veterinary medicine. In this study, the interaction of bovicin HC5 with lipid II was examined using… (More)
DOI: 10.1128/AAC.00295-12


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