Interaction with general transcription factor IIF (TFIIF) is required for the suppression of activated transcription by RPB5-mediating protein (RMP)

@article{Wei2003InteractionWG,
  title={Interaction with general transcription factor IIF (TFIIF) is required for the suppression of activated transcription by RPB5-mediating protein (RMP)},
  author={Wenxiang Wei and Jun Gu and Cui Zhu and Feng Sun and Dorjbal Dorjsuren and Yong Lin and Seishi Murakami},
  journal={Cell Research},
  year={2003},
  volume={13},
  pages={111-120}
}
ABSTRACTRMP was reported to regulate transcription via competing with HBx to bind the general transcription factor IIB (TFIIB) and interacting with RPB5 subunit of RNA polymerase II as a corepressor of transcription regulator. However, our present research uncovered that RMP also regulates the transcription through interaction with the general transcription factors IIF (TFIIF), which assemble in the preinitiation complex and function in both transcription initiation and elongation. With in… CONTINUE READING
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