Interaction with culture medium components, cellular uptake and intracellular distribution of cobalt nanoparticles, microparticles and ions in Balb/3T3 mouse fibroblasts.

@article{Sabbioni2014InteractionWC,
  title={Interaction with culture medium components, cellular uptake and intracellular distribution of cobalt nanoparticles, microparticles and ions in Balb/3T3 mouse fibroblasts.},
  author={Enrico Sabbioni and Salvador Fortaner and Massimo Farina and Riccardo del Torchio and Claudia Petrarca and Giovanni Bernardini and Renato Mariani-Costantini and Silvia Perconti and Luca Di Giampaolo and Rosalba Gornati and Mario Di Gioacchino},
  journal={Nanotoxicology},
  year={2014},
  volume={8 1},
  pages={88-99}
}
The mechanistic understanding of nanotoxicity requires the physico-chemical characterisation of nanoparticles (NP), and their comparative investigation relative to the corresponding ions and microparticles (MP). Following this approach, the authors studied the dissolution, interaction with medium components, bioavailability in culture medium, uptake and intracellular distribution of radiolabelled Co forms (CoNP, CoMP and Co(2+)) in Balb/3T3 mouse fibroblasts. Co(2+) first saturates the binding… CONTINUE READING
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