Interaction study of pioglitazone with albumin by fluorescence spectroscopy and molecular docking.


Pioglitazone is a medicine of thiazolidinedione (TZD) class with hypoglycemic (antihyperglycemic, antidiabetic) action. Pioglitazone binding to human serum albumin (HSA) was investigated at different temperatures (290, 300 and 310 K) by fluorescence spectroscopic method. Molecular docking study was also carried out besides the experiments. Experimental… (More)
DOI: 10.1016/j.saa.2010.09.001


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