Interaction study of ciprofloxacin with human telomeric DNA by spectroscopy and molecular docking.

Abstract

The interaction of ciprofloxacin (CIP) with human telomeric DNA was studied in vitro using multi-spectroscopy and molecular modeling methods. The hypochromic effect with a red shift in ultraviolet (UV) absorption indicated the occurrence of the interaction between CIP and DNA. The fluorescence quenching of CIP was observed with the addition of DNA and was… (More)
DOI: 10.1016/j.saa.2013.01.069

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