Interaction studies with moclobemide

@article{Zimmer1990InteractionSW,
  title={Interaction studies with moclobemide},
  author={Robert H. Zimmer and R. Gieschke and Rolf Fischbach and Silvio Basic},
  journal={Acta Psychiatrica Scandinavica},
  year={1990},
  volume={82}
}
Drug interactions with moclobemide given to healthy subjects and depressed patients are reviewed. The drugs investigated for safety were antihypertensives, digoxin, oral contraceptives, anticoagulants and benzodiazepines. Cimetidine was studied for the pharmacokinetic effect, and possible interactions with alcohol (stimulation and/or sedation) were included. Finally, since inhibition of monoamine oxidase (MAO) can increase noradrenergic transmission, possible interaction with neuronal reuptake… Expand
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Moclobemide is a reversible inhibitor of monoamine-oxidase-A (RIMA) and has been extensively evaluated in the treatment of a wide spectrum of depressive disorders and less extensively studied inExpand
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