Interaction potential of etravirine with drug transporters assessed in vitro.

Abstract

Etravirine is a novel nonnucleoside reverse transcriptase inhibitor (NNRTI) for the treatment of HIV-1 infections. ABC transporters potentially mediate clinically relevant drug-drug interactions. We assessed substrate characteristics and the inhibitory and inductive potential of etravirine on ABC transporters. Etravirine did not inhibit P-gp/ABCB1 and was… (More)
DOI: 10.1128/AAC.01527-10

Topics

4 Figures and Tables

Slides referencing similar topics