Interaction partners for human ZNF384/CIZ/NMP4--zyxin as a mediator for p130CAS signaling?

@article{Janssen2006InteractionPF,
  title={Interaction partners for human ZNF384/CIZ/NMP4--zyxin as a mediator for p130CAS signaling?},
  author={Hilde L K Janssen and Peter Marynen},
  journal={Experimental cell research},
  year={2006},
  volume={312 7},
  pages={1194-204}
}
Transcription factor ZNF384/CIZ/NMP4 was first cloned in rat as a p130Cas-binding protein and has a role in bone metabolism and spermatogenesis. It is recurrently involved in translocations in acute lymphoblastic leukemia. Translocations t(12;17) and t(12;22) fuse ZNF384 to RNA-binding proteins TAF15 and EWSR1, while a translocation t(12;19) generates an E2A/ZNF384 fusion. We screened for ZNF384 interacting proteins using yeast two-hybrid technology. In contrast to its rat homolog, human ZNF384… CONTINUE READING

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