Interaction of unsaturated fatty acids with anti-oestrogen-binding sites.

@article{Hwang1987InteractionOU,
  title={Interaction of unsaturated fatty acids with anti-oestrogen-binding sites.},
  author={P. L. Hwang},
  journal={The Biochemical journal},
  year={1987},
  volume={243 2},
  pages={
          359-64
        }
}
  • P. L. Hwang
  • Published 1987
  • Chemistry, Medicine
  • The Biochemical journal
Specific high-affinity binding sites for non-steroidal anti-oestrogens such as tamoxifen have been identified in many animal and human tissues. The function of these binding sites and the nature of their endogenous ligands are currently unknown. Our laboratory has previously reported that unsaturated fatty acids at micromolar concentrations inhibited [3H]tamoxifen binding to the anti-oestrogen-binding sites in rat liver, raising the possibility that fatty acids might represent endogenous… Expand
Fatty-acylation target sequence in the ligand-binding domain of vertebrate steroid receptors demarcates evolution from estrogen-related receptors
  • R. Lathe, D. Houston
  • Chemistry, Medicine
  • The Journal of Steroid Biochemistry and Molecular Biology
  • 2018
Postprandial free fatty acids stimulate activity of human corticosteroid binding globulin.
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