Interaction of unsaturated fatty acids with anti-oestrogen-binding sites.

  • P L Hwang
  • Published 1987 in The Biochemical journal

Abstract

Specific high-affinity binding sites for non-steroidal anti-oestrogens such as tamoxifen have been identified in many animal and human tissues. The function of these binding sites and the nature of their endogenous ligands are currently unknown. Our laboratory has previously reported that unsaturated fatty acids at micromolar concentrations inhibited [3H… (More)

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