Interaction of toxic and non-toxic HypF-N oligomers with lipid bilayers investigated at high resolution with atomic force microscopy

Abstract

Protein misfolded oligomers are considered the most toxic species amongst those formed in the process of amyloid formation and the molecular basis of their toxicity, although not completely understood, is thought to originate from the interaction with the cellular membrane. Here, we sought to highlight the molecular determinants of oligomer-membrane… (More)
DOI: 10.18632/oncotarget.10449

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Cite this paper

@inproceedings{OropesaNuez2016InteractionOT, title={Interaction of toxic and non-toxic HypF-N oligomers with lipid bilayers investigated at high resolution with atomic force microscopy}, author={Reinier Oropesa-Nu{\~n}ez and Silvia Seghezza and Silvia Dante and Alberto Diaspro and Roberta Cascella and Cristina Cecchi and Massimo Stefani and Fabrizio Chiti and Claudio Canale}, booktitle={Oncotarget}, year={2016} }