Interaction of the plasmid R6K-encoded replication initiator protein with its binding sites on DNA.

@article{Germino1983InteractionOT,
  title={Interaction of the plasmid R6K-encoded replication initiator protein with its binding sites on DNA.},
  author={Joseph Germino and Deepak Bastia},
  journal={Cell},
  year={1983},
  volume={34 1},
  pages={125-34}
}
Initiation of DNA replication in plasmid R6K is potentiated by the plasmid-encoded 35 kd replication initiator protein. We had previously reported that the initiator bound to two regions of R6K DNA called Site I and Site II. Using DNAase I footprinting technique we have demonstrated that the initiator bound to seven tandem repeats of a 22 bp long sequence… CONTINUE READING