Interaction of the major inflammatory bowel disease susceptibility alleles in Crohn's disease patients.

@article{Csngei2010InteractionOT,
  title={Interaction of the major inflammatory bowel disease susceptibility alleles in Crohn's disease patients.},
  author={Veronika Cs{\"o}ngei and Luca J{\'a}romi and Enikő S{\'a}fr{\'a}ny and Csilla Sipeky and Lili Magyari and Bernadett Farag{\'o} and Judit Bene and No{\'e}mi Polg{\'a}r and Lilla Lakner and Patr{\'i}cia Sarl{\'o}s and M{\'a}rta Varga and B{\'e}la Melegh},
  journal={World journal of gastroenterology},
  year={2010},
  volume={16 2},
  pages={
          176-83
        }
}
AIM To investigate the interaction of interleukin-23 receptor (IL23R) (rs1004819 and rs2201841), autophagy-related 16-like 1 (ATG16L1) (rs2241880), caspase recruitment domain-containing protein 15 (CARD15) genes, and IBD5 locus in Crohn's disease (CD) patients. METHODS A total of 315 unrelated subjects with CD and 314 healthy controls were genotyped. Interactions and specific genotype combinations of a total of eight variants were tested. The variants of IBD5 locus (IGR2198a_1 rs11739135 and… CONTINUE READING

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