Interaction of the intrinsically unstructured phage lambda N Protein with Escherichia coli NusA.

@article{Prasch2006InteractionOT,
  title={Interaction of the intrinsically unstructured phage lambda N Protein with Escherichia coli NusA.},
  author={Stefan Prasch and Sabine Schwarz and Anke Eisenmann and Birgitta M. W{\"o}hrl and Kristian Schweimer and Paul R{\"o}sch},
  journal={Biochemistry},
  year={2006},
  volume={45 14},
  pages={4542-9}
}
N protein of the Escherichia coli phage lambda (lambdaN) is involved in antitermination, a transcription regulatory process that is essential for the expression of delayed early genes during phage lytic development. lambdaN is an intrinsically unstructured protein that possesses three distinct binding sites interacting with the carboxy terminus of the E. coli host factor protein NusA, the viral nutBoxB-RNA, and RNA polymerase, respectively. Heteronuclear NMR experiments with lambdaN(1-53) in… CONTINUE READING