Interaction of the apolipoprotein E and CI loci in predisposing to late-onset Alzheimer's disease.

@article{Drigalenko1998InteractionOT,
  title={Interaction of the apolipoprotein E and CI loci in predisposing to late-onset Alzheimer's disease.},
  author={Eugene Drigalenko and Shirley E. Poduslo and Robert C. Elston},
  journal={Neurology},
  year={1998},
  volume={51 1},
  pages={131-5}
}
OBJECTIVE The association between Alzheimer's disease (AD) and alleles at the ApoE and the ApoCI loci were tested. BACKGROUND The ApoE alleles, in linkage disequlibrium with ApoCI alleles, have been reported as associated with (epsilon4) or protective for (epsilon2) AD. METHODS The patients comprise two samples, with a total of 176 whose diagnosis has been confirmed as having probable AD and 226 controls. Genomic DNA was extracted from blood or transformed lymphocytes. Logistic regression… CONTINUE READING