Interaction of the antitumor drugs phospidine and spirobromine with nucleotides

Abstract

The reactions of antitumor drugs with nucleic acids play an important role in the mechanism of their biological action [4, 12]. In developing the study of the molecular mecha i nism of the cytotoxic action of prospidine -3,12-bis(2'-hydroxy-3'chloropropyl)-3,12diaza-6,9-diazoniadispiro[5,2,5,2]hexadecane dichloride (I) -and spirobromine -3,12bis(3… (More)
DOI: 10.1007/BF00757479

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