Interaction of the adenovirus IVa2 protein with viral packaging sequences.

@article{Zhang2000InteractionOT,
  title={Interaction of the adenovirus IVa2 protein with viral packaging sequences.},
  author={Weizhen Zhang and Michael J Imperiale},
  journal={Journal of virology},
  year={2000},
  volume={74 6},
  pages={
          2687-93
        }
}
We have demonstrated previously that the adenovirus L1 52/55-kDa protein binds to the viral IVa2 protein in infected cells. The significance of this interaction was unclear, however, based on the known functions of these two proteins: the 52/55-kDa protein is required for viral DNA packaging, while the IVa2 protein is a transactivator of the major late promoter (MLP). In this report, we have attempted to elucidate a role for each of the two proteins in the other's known function. There is no… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 34 REFERENCES

Cloning, expression, and characterization of a DNA binding domain of gpNu1, a phage lambda DNA packaging protein

Q. Yang, T. de Beer, +4 authors C. E. Catalano
  • Biochemistry
  • 1999