Interaction of the Nav1.2a subunit of the voltage-dependent sodium channel with nodal ankyrinG. In vitro mapping of the interacting domains and association in synaptosomes.

@article{Bouzidi2002InteractionOT,
  title={Interaction of the Nav1.2a subunit of the voltage-dependent sodium channel with nodal ankyrinG. In vitro mapping of the interacting domains and association in synaptosomes.},
  author={Mourad Bouzidi and Nicolas Tricaud and Pierre Giraud and Ekaterini Kordeli and Ghislaine Caillol and Charlotte Deleuze and François Couraud and Gis{\'e}le Alcaraz},
  journal={The Journal of biological chemistry},
  year={2002},
  volume={277 32},
  pages={28996-9004}
}
Voltage-dependant sodium channels at the axon initial segment and nodes of Ranvier colocalize with the nodal isoforms of ankyrin(G) (Ank(G) node). Using fusion proteins derived from the intracellular regions of the Nav1.2a subunit and the Ank repeat domain of Ank(G) node, we mapped a major interaction site in the intracellular loop separating alpha subunit… CONTINUE READING