Interaction of the K(+)-channel KAT1 with the coat protein complex II coat component Sec24 depends on a di-acidic endoplasmic reticulum export motif.

@article{Sieben2008InteractionOT,
  title={Interaction of the K(+)-channel KAT1 with the coat protein complex II coat component Sec24 depends on a di-acidic endoplasmic reticulum export motif.},
  author={Christian Sieben and Melanie Mikosch and Federica Brandizzi and Ulrike Homann},
  journal={The Plant journal : for cell and molecular biology},
  year={2008},
  volume={56 6},
  pages={997-1006}
}
The correct functioning of ion channels depends not only on the control of their activity but also on the regulation of the number of channels in the membrane. For example, it has been proposed that the density of the plant K(+)-channel KAT1 may be adjusted by controlling its export from its site of synthesis, the endoplasmic reticulum (ER). Efficient transport of the channel to the plasma membrane was found to depend on a di-acidic ER export signal in the C-terminus of the protein. Studies in… CONTINUE READING