Interaction of synthetic peptide octarphin with rat myocardium membranes

@article{Nekrasova2011InteractionOS,
  title={Interaction of synthetic peptide octarphin with rat myocardium membranes},
  author={Y. N. Nekrasova and Y. Zolotarev and E. V. Navolotskaya},
  journal={Biochemistry (Moscow)},
  year={2011},
  volume={76},
  pages={1337-1341}
}
A selective agonist of non-opioid β-endorphin receptor synthetic peptide octarphin (TPLVTLFK, specific activity 28 Ci/mmol) was prepared. The [3H]octarphin binding to rat myocardium membranes before and after experimental myocardial infarction (EMI) was studied. It was found that [3H]octarphin with high affinity and specificity binds to non-opioid β-endorphin receptor of rat myocardium membranes before EMI: Kd1 value of the [3H]octarphin specific binding to membranes was 1.8 ± 0.2 nM. In 3 h… Expand
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References

SHOWING 1-10 OF 27 REFERENCES
Binding of synthetic peptide TPLVTLFK to nonopioid beta‐endorphin receptor on rat brain membranes
Characteristics of Non-opioid β-Endorphin Receptor
Binding of synthetic fragments of β‐endorphin to nonopioid β‐endorphin receptor
Specific nonopiate receptors for beta-endorphin.
...
1
2
3
...