Interaction of sigma and PCP-like drugs on operant behaviors in the rat

  title={Interaction of sigma and PCP-like drugs on operant behaviors in the rat},
  author={Thomas J. Hudzik and Barbara L. Slifer},
Many PCP-like drugs interact with at least two types of binding sites in the CNS, one of which is linked to excitatory amino acid transmission and the other with an unknown function. The present experiments were designed to further clarify the mechanism of action of drugs in this class. Assessment was made of the effects of PCP, MK-801, (+)-pentazocine, (+)- and (−)-N-allylnormetazocine (NANM), (+)-amphetamine and BMY-14802 in rats responding under a multiple timeout 600 s (TO), differential… CONTINUE READING


Publications referenced by this paper.
Showing 1-10 of 52 references

Discriminative stimulus effects of BMY-14802 in the pigeon

  • S Vanecek, W Essman, JH Woods
  • Faseb J
  • 1989
1 Excerpt

Effects of phencyclidine and other n-methyl-d-aspartate antagonists on the schedule-controlled behavior of rats

  • D JSanger, A Jackson
  • J Pharmacol Exp Ther
  • 1989

Anticonvulsant effects of PCP-like drugs: relationship to NMDA

  • JD Leander, RC Rathburn, DM Zimmerman
  • Brain Res
  • 1988

Comparison of the effects

  • KM Johnson
  • 1988

Similar Papers

Loading similar papers…