Interaction of sea cucumber saponins with multilamellar liposomes.

  title={Interaction of sea cucumber saponins with multilamellar liposomes.},
  author={Byung-soo Yu and Inho Jo},
  journal={Chemico-biological interactions},
  volume={52 2},
The effect of three sea cucumber saponins, echinoside A, bivittoside D and holothurin A, on multilamellar liposomes was investigated. An ideal osmotic behavior of liposomes was described as a linear relationship between the reciprocal 3/2 s power of absorbance at 450 nm and the osmotic gradient across the membrane. Sea cucumber saponins at concentrations below critical micelle concentration (CMC) disturbed this linear relationship in liposomes composed of egg phosphatidylcholine, phosphatidic… CONTINUE READING