Interaction of quorum signals with outer membrane lipids: insights into prokaryotic membrane vesicle formation

@article{MashburnWarren2008InteractionOQ,
  title={Interaction of quorum signals with outer membrane lipids: insights into prokaryotic membrane vesicle formation},
  author={Lauren Mashburn-Warren and Joerg Howe and Patrick Garidel and Walter Richter and Frank Steiniger and Manfred R{\"o}ssle and Klaus Brandenburg and Marvin Whiteley},
  journal={Molecular Microbiology},
  year={2008},
  volume={69},
  pages={491 - 502}
}
Bacteria have evolved elaborate communication strategies to co-ordinate their group activities, a process termed quorum sensing (QS). Pseudomonas aeruginosa is an opportunistic pathogen that utilizes QS for diverse activities, including disease pathogenesis. P. aeruginosa has evolved a novel communication system in which the signal molecule 2-heptyl-3-hydroxy-4-quinolone (Pseudomonas Quinolone Signal, PQS) is trafficked between cells via membrane vesicles (MVs). Not only is PQS packaged into… CONTINUE READING
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Signal trafficking with bacterial outer membrane vesicles

  • L. M. Mashburn-Warren, M. Whiteley
  • 2008
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