Interaction of poly-L-arginine with dihexadecyl phosphate/phosphatidylcholine liposomes.

@article{Tsogas2005InteractionOP,
  title={Interaction of poly-L-arginine with dihexadecyl phosphate/phosphatidylcholine liposomes.},
  author={Ioannis Tsogas and Dimitris Tsiourvas and George Nounesis and Constantinos M. Paleos},
  journal={Langmuir : the ACS journal of surfaces and colloids},
  year={2005},
  volume={21 13},
  pages={5997-6001}
}
In the present study, mixed liposomes of dihexadecyl phosphate sodium salt:phosphatidylcholine:cholesterol at a 1:19:9.5 molar ratio were allowed to interact with poly-L-arginine at temperatures below and above the main phase transition of the liposomal membrane. The interaction led to the formation of aggregates, which gradually increased in size and eventually precipitated. It was, however, possible, during the initial stage of the experiments, when the ratio of guanidinium group relative to… CONTINUE READING