Interaction of neuropeptide Y genotype and childhood emotional maltreatment on brain activity during emotional processing.

@article{Opmeer2014InteractionON,
  title={Interaction of neuropeptide Y genotype and childhood emotional maltreatment on brain activity during emotional processing.},
  author={Esther M. Opmeer and Rudie Kortekaas and Marie-Jos{\'e} van Tol and Nic J A van der Wee and Saskia Woudstra and Mark A. van Buchem and Brenda W Penninx and Dick J. Veltman and Andr{\'e} Alem{\'a}n},
  journal={Social cognitive and affective neuroscience},
  year={2014},
  volume={9 5},
  pages={
          601-9
        }
}
Neuropeptide Y (NPY) has been associated with stress reactivity in affective disorders and is most densely expressed in the amygdala. An important stressor associated with affective disorders is the experience of childhood emotional maltreatment (CEM). We investigated whether the interaction of NPY risk genotype and CEM would affect brain activation. From The Netherlands Study of Depression and Anxiety, 33 healthy controls and 85 patients with affective disorders were scanned with functional… CONTINUE READING
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