Interaction of nalbuphine hydrochloride with deoxyribonucleic acid measured by fluorescence quenching.

Abstract

The interaction of nalbuphine hydrochloride with calf thymus deoxyribonucleic acid was investigated by absorption and fluorescence titration techniques. Hypochromic effect was observed in the absorption spectra of nalbuphine. The fluorescence quenching of nalbuphine by DNA was found to be static according to Stern-Volmer constant at different temperature (2… (More)
DOI: 10.1055/s-0033-1334874

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