Interaction of metabolites with R. rhodochrous during the biodegradation of di-ester plasticizers.

@article{Nalli2006InteractionOM,
  title={Interaction of metabolites with R. rhodochrous during the biodegradation of di-ester plasticizers.},
  author={Sandro Nalli and David G. Cooper and Jim A. Nicell},
  journal={Chemosphere},
  year={2006},
  volume={65 9},
  pages={1510-7}
}
The commonly used plasticizers di-ethylhexyl phthalate (DEHP) and di-ethylhexyl adipate (DEHA) are known to partially degrade in the presence of soil microorganisms, such as Rhodococcus rhodochrous, releasing persistent and toxic metabolites. The metabolites adipic acid and 2-ethylhexanol were both shown to inhibit growth of the degrading microbe. 2-Ethylhexanol enhanced the activity of ethanol dehydrogenase - an enzyme involved in its metabolism - but the activity of this enzyme was inhibited… CONTINUE READING
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