Interaction of magnesium sulphate with vecuronium-induced neuromuscular block.

@article{FuchsBuder1995InteractionOM,
  title={Interaction of magnesium sulphate with vecuronium-induced neuromuscular block.},
  author={Thomas Fuchs-Buder and Oliver H. G. Wilder-Smith and Alain Borgeat and Ed{\"o}m{\'e}r Tassonyi},
  journal={British journal of anaesthesia},
  year={1995},
  volume={74 4},
  pages={
          405-9
        }
}
We have investigated the interaction between magnesium sulphate 40 mg kg-1 i.v. and vecuronium. First, we determined the effect of pretreatment with magnesium on the potency of vecuronium using a single bolus dose-response technique. In addition, we compared the time course of vecuronium-induced neuromuscular block (vecuronium 100 micrograms kg-1) with and without magnesium pretreatment. For both parts, neuromuscular block was assessed by electromyography. In addition, the effect of magnesium… Expand
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