Interaction of lipopolysaccharides and lipid A with complement in rats and its relation to endotoxicity.


Uniform salt forms of endotoxic lipopolysaccharides (LPS) and free lipid A showing distinct differences in their anticomplementary activity, as well as a nontoxic LPS, are used in a new approach of studying the role of complement in endotoxin shock. The use of these defined LPS forms led to the identification of two timely, distinct depressions in… (More)


7 Figures and Tables