Interaction of iron with polyphenolic compounds: application to antioxidant characterization.

@article{Yoshino1998InteractionOI,
  title={Interaction of iron with polyphenolic compounds: application to antioxidant characterization.},
  author={Masataka Yoshino and Keiko Murakami},
  journal={Analytical biochemistry},
  year={1998},
  volume={257 1},
  pages={
          40-4
        }
}
Antioxidant action of flavonoids and polyphenolics was analyzed in relation to iron coordination. Flavonoids including baicalein, baicalin, quercetin, and rutin showed little or no reducing activity, and enhanced the autooxidation of Fe2+ ion. Ascorbate-mediated reduction of iron was rather inhibited by flavonoids. Nonflavonoid polyphenolics such as protocatechuic acid and chlorogenic acid, on the contrary, showed a potent iron-reducing ability, and protected Fe2+ ion from autooxidation… 
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