Interaction of integrin receptors with extracellular matrix is involved in trophoblast giant cell migration in bovine placentomes.

@article{Pfarrer2003InteractionOI,
  title={Interaction of integrin receptors with extracellular matrix is involved in trophoblast giant cell migration in bovine placentomes.},
  author={Christiane Pfarrer and Pierre Hirsch and Michel Guillomot and Rudolf Leiser},
  journal={Placenta},
  year={2003},
  volume={24 6},
  pages={588-97}
}
Integrins are heterodimeric glycoproteins involved in cell-cell and cell-extracellular matrix adhesion and signal transduction. We evaluated the distribution and the putative role of integrin receptors and extracellular matrix (ECM) proteins during trophoblast giant cell (TGC) migration and fusion with uterine epithelial cells in the cow. Placentomes from 24 cows, covering day 80 to day 270 of gestation, were used for indirect immunohistochemistry against integrin subunits alpha(1), alpha(2… CONTINUE READING
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