Interaction of insulin with Pseudomonas pseudomallei.

  title={Interaction of insulin with Pseudomonas pseudomallei.},
  author={Donald E. Woods and Amanda L Jones and Philip J. Hill},
  journal={Infection and immunity},
  volume={61 10},
Pseudomonas pseudomallei is the causative agent of melioidosis, a disease being increasingly recognized as an important cause of morbidity and mortality in many regions of the world. An intriguing observation regarding melioidosis is that a significant percentage of patients who develop the disease have preexisting diabetes mellitus. In this regard, we have tested the hypothesis that insulin may modulate the growth of P. pseudomallei. We have demonstrated that insulin markedly inhibits the… CONTINUE READING


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