Interaction of hormone-sensitive lipase with steroidogenic acute regulatory protein: facilitation of cholesterol transfer in adrenal.

@article{Shen2003InteractionOH,
  title={Interaction of hormone-sensitive lipase with steroidogenic acute regulatory protein: facilitation of cholesterol transfer in adrenal.},
  author={Wen-Jun Shen and Shailja Patel and Vanita S Natu and Richard Hong and Jenny Z Wang and Salman Azhar and Fredric B Kraemer},
  journal={The Journal of biological chemistry},
  year={2003},
  volume={278 44},
  pages={43870-6}
}
Hormone-sensitive lipase (HSL) is responsible for the neutral cholesteryl ester hydrolase activity in steroidogenic tissues. Through its action, HSL is involved in regulating intracellular cholesterol metabolism and making unesterified cholesterol available for steroid hormone production. Steroidogenic acute regulatory protein (StAR) facilitates the movement of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane and is a critical regulatory step in… CONTINUE READING

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