Interaction of hepatitis C virus core protein with viral sense RNA and suppression of its translation.

@article{Shimoike1999InteractionOH,
  title={Interaction of hepatitis C virus core protein with viral sense RNA and suppression of its translation.},
  author={Takashi Shimoike and S Mimori and Hideki Tani and Yoshiharu Matsuura and Tatsuo Miyamura},
  journal={Journal of virology},
  year={1999},
  volume={73 12},
  pages={9718-25}
}
To clarify the binding properties of hepatitis C virus (HCV) core protein and its viral RNA for the encapsidation, morphogenesis, and replication of HCV, the specific interaction of HCV core protein with its genomic RNA synthesized in vitro was examined in an in vivo system. The positive-sense RNA from the 5' end to nucleotide (nt) 2327, which covers the 5' untranslated region (5'UTR) and a part of the coding region of HCV structural proteins, interacted with HCV core protein, while no… CONTINUE READING
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