Interaction of gephyrotoxin and indolizidine alkaloids with the nicotinic acetylcholine receptorion channel complex of torpedo electroplax

Abstract

The interactions of eighteen natural and synthetic gephyrotoxin and indolizidine alkaloids with binding sites on nicotinic acetylcholine receptor channel (AChR) complex fromTorpedo californica electric organ were investigated using two radiolabeled probes, [3H]perhydrohistrionicotoxin and [3H]phencyclidine. Both gephyrotoxins and indolizidines were… (More)
DOI: 10.1007/BF00965950

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