Interaction of flavodoxin with cobalamin-dependent methionine synthase.

Abstract

Cobalamin-dependent methionine synthase catalyzes the transfer of a methyl group from methyltetrahydrofolate to homocysteine, forming tetrahydrofolate and methionine. The Escherichia coli enzyme, like its mammalian homologue, is occasionally inactivated by oxidation of the cofactor to cob(II)alamin. To return to the catalytic cycle, the cob(II)alamin forms… (More)

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@article{Hall2000InteractionOF, title={Interaction of flavodoxin with cobalamin-dependent methionine synthase.}, author={D. A. Hall and T C Jordan-Starck and R O Loo and Mike Ludwig and Robert Matthews}, journal={Biochemistry}, year={2000}, volume={39 35}, pages={10711-9} }