Interaction of ethanol with biological membranes.

@article{Goldstein1981InteractionOE,
  title={Interaction of ethanol with biological membranes.},
  author={Dora B. Goldstein and Jane Heng Chin},
  journal={Federation proceedings},
  year={1981},
  volume={40 7},
  pages={2073-6}
}
Ethanol is among the drugs with anesthetic potency determined by lipid solubility, in accord with the Meyer-Overton hypothesis. Thus, it is likely that ethanol acts in a hydrophobic environment. Using electron paramagnetic resonance with 5-doxylstearic acid as spin label, we find that ethanol disorders mouse cell membranes, making the lipid matrix more… CONTINUE READING