Interaction of ethanol with acetaminophen metabolism in the baboon.

Abstract

To evaluate the effects of ethanol on acetaminophen metabolism and toxicity, twelve female baboons were studied using three experimental designs. In the first one, animals fed ethanol chronically and their pair-fed controls received acetaminophen intravenously (40 mg/kg), and drug metabolism was studied for 6 hr in blood and urine. Elimination of… (More)

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Cite this paper

@article{Altomare1984InteractionOE, title={Interaction of ethanol with acetaminophen metabolism in the baboon.}, author={Emanuela Altomare and M. A. S. Di Leo and Chifumi Sato and Gianluigi Vendemiale and Colette Lieber}, journal={Biochemical pharmacology}, year={1984}, volume={33 14}, pages={2207-12} }