Interaction of estramustine phosphate with microtubule-associated proteins.

@article{Wallin1985InteractionOE,
  title={Interaction of estramustine phosphate with microtubule-associated proteins.},
  author={Margareta Wallin and Johanna Deinum and Bo Frid{\'e}n},
  journal={FEBS letters},
  year={1985},
  volume={179 2},
  pages={289-93}
}
We have reported [(1984) Cancer Res., in press] that estramustine phosphate inhibits microtubule assembly and disassembled preformed microtubules. We now present evidence that estramustine phosphate inhibits microtubule assembly by binding to the microtubule-associated proteins. We have found that: additional microtubule-associated proteins relieved the inhibition of assembly by estramustine phosphate; 3H-labelled estramustine phosphate bound predominantly to the microtubule-associated proteins… CONTINUE READING

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