Interaction of epicatechins derived from green tea with rat hepatic cytochrome P-450.

@article{Wang1988InteractionOE,
  title={Interaction of epicatechins derived from green tea with rat hepatic cytochrome P-450.},
  author={Z Y Wang and M S Maya Das and David R. Bickers and Hasan Mukhtar},
  journal={Drug metabolism and disposition: the biological fate of chemicals},
  year={1988},
  volume={16 1},
  pages={98-103}
}
Green tea has been used for generations in China and Asia as an antipyretic and diuretic. Prior studies have shown that extracts of green tea inhibit the mutagenicity of polycyclic aromatic hydrocarbons and aflatoxin B1. In this study, we investigated the interaction of certain flavonoid components of green tea epicatechin derivatives including (-)-epicatechin (EC), (-)-epigallocatechin (EGC), (-)-epicatechin-3-gallate (ECG), and (-)-epigallocatechin-3-gallate (EGCG) with rat hepatic microsomal… CONTINUE READING

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