Interaction of cycloalkanoprogesterones with mammalian progesterone receptor: binding of pregna-D'-pentaranes in the calf uterine cytosol

@article{Bhakta2004InteractionOC,
  title={Interaction of cycloalkanoprogesterones with mammalian progesterone receptor: binding of pregna-D'-pentaranes in the calf uterine cytosol},
  author={A. Bhakta and M. Herman and I. S. Levina and V. Moudgil},
  journal={Molecular and Cellular Biochemistry},
  year={2004},
  volume={125},
  pages={153-161}
}
Pregna-D'-pentaranes (pentaranes) are modified progesterones with demonstrable progestational activity and contraceptive effect. We have examined the steroid binding characteristics of the two newly synthesized progesterone analogs, Pentarane A (16α, 17α-cyclohexanoprogesterone) and Pentarane B (6α-methyl, 16α, 17α-cyclohexanoprogesterone), and studied the nature of their interaction with progesterone receptor (PR) from the chicken oviduct and the calf uterine cytosols. Pregna-D'-pentaranes… Expand
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