Interaction of classical swine fever virus with membrane-associated heparan sulfate: role for virus replication in vivo and virulence.

@article{Hulst2001InteractionOC,
  title={Interaction of classical swine fever virus with membrane-associated heparan sulfate: role for virus replication in vivo and virulence.},
  author={Marcel Hulst and H. G. P. van Gennip and A Corina Vlot and E. J. van Schooten and Abraham J. de Smit and Rob J. M. Moormann},
  journal={Journal of virology},
  year={2001},
  volume={75 20},
  pages={
          9585-95
        }
}
Passage of native classical swine fever virus (CSFV) in cultured swine kidney cells (SK6 cells) selects virus variants that attach to the surface of cells by interaction with membrane-associated heparan sulfate (HS). A Ser-to-Arg change in the C terminus of envelope glycoprotein E(rns) (amino acid 476 in the open reading frame of CSFV) is responsible for selection of these HS-binding virus variants (M. M. Hulst, H. G. P. van Gennip, and R. J. M. Moormann, J. Virol. 74:9553-9561, 2000). In this… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 33 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 53 REFERENCES

Molecular cloning and nucleotide sequence of hog cholera virus strain Brescia and mapping of the genomic region encoding envelope protein

Moormann, M R.J., +4 authors M. M. Hulst
  • Virology
  • 1990
VIEW 10 EXCERPTS
HIGHLY INFLUENTIAL

Interaction of glycoprotein E of classical swine fever virus with the cell surface, P2/3-1

M. M. Hulst, R.J.M. Moormann
  • 1999

Similar Papers

Loading similar papers…